3,728 research outputs found
Recent Evolution of Glaciers in the Manaslu Region of Nepal From Satellite Imagery and UAV Data (1970–2019)
Glacierized mountain ranges such as the Himalaya comprise a variety of glacier types, including clean and debris-covered glaciers. Monitoring their behaviour over time requires an assessment of changes in area and elevation along with surface features and geomorphology. In this paper we quantify the surface evolution of glacier systems in the Manaslu region of Nepal over the last five decades using 2013/2019 multi-sensor imagery and elevation data constructed from 1970 declassified Corona imagery and 1970 declassified Corona imagery. We investigate area changes, glacier thickness, geodetic glacier mass balance and surface velocity changes at regional scales and focus on the Ponkar Glacier and Thulagi Glacier and Lake for an in-depth assessment of surface geomorphology and surface feature dynamics (ponds, vegetation and ice cliffs). The time series of surface elevation changes for the lower ablation area of Ponkar Glacier is extended using 2019 UAV-based imagery and field-based ablation rates measured over the period 2016–2019. Glaciers in the Manaslu region experienced a mean area loss of −0.26 ± 0.0001% a−1 between 1970 and 2019. The mean surface lowering was −0.20 ± 0.02 ma−1 over the period 1970 to 2013, corresponding to a regional geodetic mass balance of −0.17 ± 0.03 m w. e.a−1. Overall, debris-covered glaciers had slightly higher thinning rates compared to clean ice glaciers; lake-terminating glaciers had double thinning rates compared to land-terminating glaciers. Individual glacier mass balance was negatively controlled by glacier slope and mean glacier elevation. During the period 1970 to 2013, Ponkar Glacier had a geodetic mass balance of −0.06 ± 0.01 m w. e.a−1, inversely correlated with parts of the central trunk thickening. Between 2013 and 2019 there was a nine-fold increase in the thinning rates over the lower parts of the glacier tongue relative to the period 1970–2013. Ice-surface morphology changes between 1970 and 2019 on Ponkar Glacier include a decrease in ogives and open crevasses, an increase in ice cliffs and ponds and the expansion of the supraglacial debris and ice-surface vegetation. These changes point to reduced ice-dynamic activity and are commensurate with the observed recession and negative glacier mass balance over the last five decades.publishedVersio
Data production models for the CDF experiment
The data production for the CDF experiment is conducted on a large Linux PC
farm designed to meet the needs of data collection at a maximum rate of 40
MByte/sec. We present two data production models that exploits advances in
computing and communication technology. The first production farm is a
centralized system that has achieved a stable data processing rate of
approximately 2 TByte per day. The recently upgraded farm is migrated to the
SAM (Sequential Access to data via Metadata) data handling system. The software
and hardware of the CDF production farms has been successful in providing large
computing and data throughput capacity to the experiment.Comment: 8 pages, 9 figures; presented at HPC Asia2005, Beijing, China, Nov 30
- Dec 3, 200
Data processing model for the CDF experiment
The data processing model for the CDF experiment is described. Data
processing reconstructs events from parallel data streams taken with different
combinations of physics event triggers and further splits the events into
datasets of specialized physics datasets. The design of the processing control
system faces strict requirements on bookkeeping records, which trace the status
of data files and event contents during processing and storage. The computing
architecture was updated to meet the mass data flow of the Run II data
collection, recently upgraded to a maximum rate of 40 MByte/sec. The data
processing facility consists of a large cluster of Linux computers with data
movement managed by the CDF data handling system to a multi-petaByte Enstore
tape library. The latest processing cycle has achieved a stable speed of 35
MByte/sec (3 TByte/day). It can be readily scaled by increasing CPU and
data-handling capacity as required.Comment: 12 pages, 10 figures, submitted to IEEE-TN
Selection at a single locus leads to widespread expansion of toxoplasma gondii lineages that are virulent in mice
The determinants of virulence are rarely defined for eukaryotic parasites such as T. gondii, a widespread parasite of mammals that also infects humans, sometimes with serious consequences. Recent laboratory studies have established that variation in a single secreted protein, a serine/threonine kinase known as ROPO18, controls whether or not mice survive infection. Here, we establish the extent and nature of variation in ROP18among a collection of parasite strains from geographically diverse regions. Compared to other genes, ROP18 showed extremely high levels of diversification and changes in expression level, which correlated with severity of infection in mice. Comparison with an out-group demonstrated that changes in the upstream region that regulates expression of ROP18 led to an historical increase in the expression and exposed the protein to diversifying selective pressure. Surprisingly, only three atypically distinct protein variants exist despite marked genetic divergence elsewhere in the genome. These three forms of ROP18 are likely adaptations for different niches in nature, and they confer markedly different virulence to mice. The widespread distribution of a single mouse-virulent allele among geographically and genetically disparate parasites may have consequences for transmission and disease in other hosts, including humans
Reduced Retinal Function in the Absence of Nav1.6
Background: Mice with a function-blocking mutation in the Scn8a gene that encodes Nav1.6, a voltage-gated sodium channel (VGSC) isoform normally found in several types of retinal neurons, have previously been found to display a profoundly abnormal dark adapted flash electroretinogram. However the retinal function of these mice in light adapted conditions has not been studied. Methodology/Principal Findings: In the present report we reveal that during light adaptation these animals are shown to have electroretinograms with significant decreases in the amplitude of the a- and b-waves. The percent decrease in the a-and b-waves substantially exceeds the acute effect of VGSC block by tetrodotoxin in control littermates. Intravitreal injection of CoCl 2 or CNQX to isolate the a-wave contributions of the photoreceptors in littermates revealed that at high background luminance the cone-isolated component of the a-wave is of the same amplitude as the a-wave of mutants. Conclusions/Significance: Our results indicate that Scn8a mutant mice have reduced function in both rod and the cone retinal pathways. The extent of the reduction in the cone pathway, as quantified using the ERG b-wave, exceeds the reduction seen in control littermates after application of TTX, suggesting that a defect in cone photoreceptors contributes to the reduction. Unless the postreceptoral component of the a-wave is increased in Scn8a mutant mice, the reduction in the b-wave is larger than can be accounted for by reduced photoreceptor function alone. Our data suggests that th
Evidence for t\bar{t}\gamma Production and Measurement of \sigma_t\bar{t}\gamma / \sigma_t\bar{t}
Using data corresponding to 6.0/fb of ppbar collisions at sqrt(s) = 1.96 TeV
collected by the CDF II detector, we present a cross section measurement of
top-quark pair production with an additional radiated photon. The events are
selected by looking for a lepton, a photon, significant transverse momentum
imbalance, large total transverse energy, and three or more jets, with at least
one identified as containing a b quark. The ttbar+photon sample requires the
photon to have 10 GeV or more of transverse energy, and to be in the central
region. Using an event selection optimized for the ttbar+photon candidate
sample we measure the production cross section of, and the ratio of cross
sections of the two samples. Control samples in the dilepton+photon and
lepton+photon+\met, channels are constructed to aid in decay product
identification and background measurements. We observe 30 ttbar+photon
candidate events compared to the standard model expectation of 26.9 +/- 3.4
events. We measure the ttbar+photon cross section to be 0.18+0.08 pb, and the
ratio of the cross section of ttbar+photon to ttbar to be 0.024 +/- 0.009.
Assuming no ttbar+photon production, we observe a probability of 0.0015 of the
background events alone producing 30 events or more, corresponding to 3.0
standard deviations.Comment: 9 pages, 3 figure
Precision Top-Quark Mass Measurements at CDF
We present a precision measurement of the top-quark mass using the full
sample of Tevatron TeV proton-antiproton collisions collected
by the CDF II detector, corresponding to an integrated luminosity of 8.7
. Using a sample of candidate events decaying into the
lepton+jets channel, we obtain distributions of the top-quark masses and the
invariant mass of two jets from the boson decays from data. We then compare
these distributions to templates derived from signal and background samples to
extract the top-quark mass and the energy scale of the calorimeter jets with
{\it in situ} calibration. The likelihood fit of the templates from signal and
background events to the data yields the single most-precise measurement of the
top-quark mass, \mtop = 172.85 \pm\pmComment: submitted to Phys. Rev. Let
Observation of Exclusive Gamma Gamma Production in p pbar Collisions at sqrt{s}=1.96 TeV
We have observed exclusive \gamma\gamma production in proton-antiproton
collisions at \sqrt{s}=1.96 TeV, using data from 1.11 \pm 0.07 fb^{-1}
integrated luminosity taken by the Run II Collider Detector at Fermilab. We
selected events with two electromagnetic showers, each with transverse energy
E_T > 2.5 GeV and pseudorapidity |\eta| < 1.0, with no other particles detected
in -7.4 < \eta < +7.4. The two showers have similar E_T and azimuthal angle
separation \Delta\phi \sim \pi; 34 events have two charged particle tracks,
consistent with the QED process p \bar{p} to p + e^+e^- + \bar{p} by two-photon
exchange, while 43 events have no charged tracks. The number of these events
that are exclusive \pi^0\pi^0 is consistent with zero and is < 15 at 95% C.L.
The cross section for p\bar{p} to p+\gamma\gamma+\bar{p} with |\eta(\gamma)| <
1.0 and E_T(\gamma) > 2.5$ GeV is
2.48^{+0.40}_{-0.35}(stat)^{+0.40}_{-0.51}(syst) pb.Comment: 7 pages, 4 figure
A search for resonant production of pairs in $4.8\ \rm{fb}^{-1}p\bar{p}\sqrt{s}=1.96\ \rm{TeV}$
We search for resonant production of tt pairs in 4.8 fb^{-1} integrated
luminosity of ppbar collision data at sqrt{s}=1.96 TeV in the lepton+jets decay
channel, where one top quark decays leptonically and the other hadronically. A
matrix element reconstruction technique is used; for each event a probability
density function (pdf) of the ttbar candidate invariant mass is sampled. These
pdfs are used to construct a likelihood function, whereby the cross section for
resonant ttbar production is estimated, given a hypothetical resonance mass and
width. The data indicate no evidence of resonant production of ttbar pairs. A
benchmark model of leptophobic Z \rightarrow ttbar is excluded with m_{Z'} <
900 GeV at 95% confidence level.Comment: accepted for publication in Physical Review D Sep 21, 201
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